Optune Gio® Tumour-Treating Field Therapy

What were we asked to look at?

We were asked to summarise the evidence on Optune®. Optune® is an innovative, portable and non-invasive device designed to prolong survival and slow disease progression in individuals with glioblastoma, IDH-wildtype. It generates alternating electrical fields, known as TTFields, which are delivered via electrodes called transducer arrays attached to a person's shaved scalp. 

Why is this important?

Glioblastomas are a fast-growing type of brain tumour, and are the most common type of cancerous (malignant) brain tumour in adults. The current standard of care is surgery, radiotherapy and chemotherapy. Despite maximal treatment, the long-term prognosis of glioblastomas is poor, and average overall survival time is 12 to 18 months. If the evidence shows that Optune® can prolong survival in patients with glioblastoma, it could potentially offer an additional treatment option for this difficult-to-treat cancer. 

Referred by

Novocure UK Ltd.

Health service organisation and delivery

IMTO

29 April 2025

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